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The telegraph

All adults can reduce the risk of a heart attack with the daily blood pressure pill

One study found that all adults would benefit from taking a blood pressure pill every day to reduce their risk of heart attack and stroke. The Oxford University major review concluded that lowering blood pressure was protective even when it was within the considered healthy range. In what is known as a "paradigm shift," the review found that a daily dose reduced the risk of severe cardiovascular disease by about 10 percent. The results were the same regardless of a person's blood pressure at the start of the study. The results, published in The Lancet, show that potentially millions of people currently ineligible could benefit from antihypertensive drugs, including commonly prescribed drugs like ramipril, which is sold under the brand name Altace, amlodipine, and various beta-blockers. According to the British Heart Foundation, around 14 million people in the UK have high blood pressure, of which five million are believed to have the disease. Medical guidelines indicate that normally only people with high blood pressure (over 140/90 mmHg) should be considered for antihypertensive drugs. However, the new study of 340,000 people in 48 randomized clinical trials found that the size of a person's relative rise or fall in blood pressure was more likely to determine a person's risk of a heart attack or stroke than the level itself. The authors called for a change in guidelines so that people are not prevented from receiving antihypertensive drugs just because their blood pressure is not high enough or because they have not previously had a cardiovascular event. Professor Kazem Rahimi, who led the research, told the Telegraph, "Antihypertensive drugs are a preventative measure regardless of their blood pressure. Many people who need them are unlikely to be given them." Encouraging all adults to showcase the Pilules, the authors reiterate that they have important financial implications for the NHS and that the inconvenient benefits to import and the benefits to people are a real risk for cardiovascular disease. Mais le professeur Rahimi ajouté: "At the population level, in moyenne you will get a relative risk reduction of 10 g cents if you traitez tout le monde. C'est general - mais c'est avant de prendre en compte d ' other things. "He said that many patients currently on antihypertensive drugs are taking a combination, often up to three drugs per day, which means the protective effect is significantly greater. And he added that doctors should ignore seemingly healthy blood pressure when choosing to prescribe medication and instead assess a patient's risk of heart attack and stroke based on factors such as cholesterol levels, age, and signs of diabetes. Heart disease and stroke are the leading causes of death in much of the western world, and it is widely believed that high blood pressure drugs prevent people who have already had one event from having a second. However, the use of these drugs in people with normal or slightly elevated blood pressure has been hotly debated and studies have produced conflicting results. For the new analysis, the experts combined data from 157,728 participants with a previous diagnosis of cardiovascular disease and 186,988 without such a diagnosis. Each group was then divided into seven subgroups based on systolic blood pressure. After four years of follow-up, 42,324 participants had at least one major cardiovascular event. For every 5 mmHg decrease in systolic blood pressure, the risk of stroke or heart failure decreased by 13%, ischemic heart disease by 8%, and death from cardiovascular disease by 5%. The beneficial effects of treatment did not differ depending on whether the person had previously had cardiovascular disease. Zeinab Bidel, co-author and also from Oxford, said, "It is important that people be considered for antihypertensive therapy because of their cardiovascular risk, rather than focusing on blood pressure itself as a factor. Suitable or target for treatment . " We need to put in place balanced guidelines to reduce the risk of cardiovascular disease, including exercise, diet, smoking cessation and, where appropriate, medication. "Professor Sir Nilesh Samani, Medical Director of the British Heart Foundation, who was not involved in the study, said," The benefits of lowering blood pressure exist whether or not you already have heart disease, and this study shows that lowering does Your blood pressure is available Blood pressure Even if blood pressure is within the normal range, it is associated with fewer heart attacks and strokes. "

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